Modafinil in Endozepine Stupor. A Case Report
نویسندگان
چکیده
منابع مشابه
Modafinil in endozepine stupor. A case report.
BACKGROUND Endozepine-4 stupor is a rare disorder. It presents with recurrent episodes of stupor and coma. Endozepine-4 levels are elevated during an attack with electroencephalogram showing fast activity during the ictal phase. There is no specific treatment and various drugs have been tried without long-term benefit. METHOD We used the vigilance promoting drug modafinil to prevent such atta...
متن کاملEndozepine stupor. Recurring stupor linked to endozepine-4 accumulation.
Recurring stupor can be caused by repeated metabolic, toxic or structural brain disturbances. Recently, cases of recurring stupor, with fast EEG activity were shown to display increased endogenous benzodiazepine-like activity during the episodes of stupor. Patients with recurring stupor underwent extensive metabolic and toxicologic screening, EEG and brain imaging. Endozepines and exogenously a...
متن کاملSuspected covert lorazepam administration misdiagnosed as recurrent endozepine stupor.
We recently reported in Brain (Lugaresi et al., 1998) 20 cases of idiopathic recurrent stupor due to endozepine-4 accumulation in the blood. Samples obtained from nine of these patients were analysed by gas chromatography–mass spectrometry to rule out contaminating synthetic benzodiazepines (Rothstein et al., 1992). All these samples contained endozepine-4 concentrations high enough to account ...
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Modafinil is used in the treatment of excessive day time sleepiness associated with several clinical conditions. It can also be used for affective stimulation for working late and/or concentrating for a long time. The reported cases of psychosis associated with modafinil use in the literature, have medical or psychiatric diorders. There is only one reported case without medical or psychiatric d...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 2004
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100003541